This Podcast features an interview with Christopher Ward, Ramzi Khairallah, and Eric Hoffman, authors of a Research Article published in the 7 August 2012 issue of Science Signaling. Duchenne muscular dystrophy (DMD) is an inherited, degenerative muscle disease that is caused by mutations in the gene that encodes dystrophin, which is part of the cytoskeleton in muscle cells. DMD is a progressive disease that causes muscle weakness, leading to paralysis and eventually death. In a mouse model of D
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