This Podcast features a conversation with the senior author of a Report published in the 4 May 2012 issue of Science. Mark Nelson discusses his group’s use of a biosensor to investigate calcium (Ca2+) signaling in the endothelial cells that line arteries. Ca2+ signaling in endothelial cells is critical for their ability to regulate the function of the underlying vascular smooth muscle cells. Contraction and dilation of the smooth muscle cells control blood vessel diameter, which is importa
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