Access to the article is free, however registration and sign-in are required. One way by which cells in the intestinal milieu may prevent this possible outcome is to apply a number of checks on the resident microflora that control its overall size and composition. Cash et al. characterize one such check--the ability of epithelial cells lining parts of the mucosa to produce RegIII (regenerating islet 3 gamma), a C-type lectin with bactericidal properties. This substance may not only regulate the
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